凹凸山区蓝桥埠镇村民姜大牙（张丰毅饰）在迎亲路上，遭遇日军轰炸，全村只有他、新娘子韩春云（李琳饰）、同乡陈墨涵（孙松饰）和朱预道（林永健饰）四人侥幸逃生。在人生选择上，姜大牙和朱预道想投国民党，却进了新四军的队伍；而陈墨涵和韩春云想投新四军，却被国民党抓差。他们的人生境遇从此更改：在司令员杨庭辉（李雪健饰）的栽培下，姜大牙成长为一名新四军将领，但是他的劣习却引来了部分同志的意见：张普景觉得他思想觉悟不够，窦玉泉觉得他资历尚浅。而江古碑（于和伟饰）则嫌他对宣传干事东方闻音（殷桃饰）示爱，从此怀恨在心，这令姜大牙的遭受了不少坎坷。与此同时，陈墨涵与韩春云也在国民党军队中找到了各自的位置。昔日的同乡，时敌时友，随时势而变……本片刻画了各位主人公自抗战至文革长达四十多年的人生际遇。
本片根据徐贵祥同名小说改编，该书曾获得第六届“茅盾文学奖”。
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